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Delays Induce Novel Stochastic Effects in Negative Feedback Gene Circuits

Stochastic models of reaction networks are widely used to depict gene expression dynamics. However, stochastic does not necessarily imply accurate, as subtle assumptions can yield erroneous results, masking key discrete effects. For instance, transcription and translation are not instantaneous proce...

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Detalhes bibliográficos
Main Authors: Zavala, Eder, Marquez-Lago, Tatiana T.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907244/
https://ncbi.nlm.nih.gov/pubmed/24461022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.12.010
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