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Annulated Diketopiperazines from Dipeptides or Schöllkopf Reagents via Tandem Cyclization-Intramolecular N-Arylation
[Image: see text] Facile CuI-mediated N-arylation of diketopiperazine using the Fukuyama modification of the Ullmann-Goldberg reaction can be exploited in new approaches to enantio-pure polycyclic diketopiperazines from easily assembled dipeptides or functionalized Schöllkopf reagents.
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862128/ https://ncbi.nlm.nih.gov/pubmed/20387855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol100663y |
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