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The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression
Despite advances in defining the critical molecular determinants for leukemia stem cell (LSC) generation and maintenance, little is known about the roles of microRNAs in LSC biology. Here we identify microRNAs that are differentially expressed in LSC-enriched cell fractions (c-kit(+)) in a mouse mod...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
2010
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862107/ https://ncbi.nlm.nih.gov/pubmed/20406979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3268 |
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