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The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression

Despite advances in defining the critical molecular determinants for leukemia stem cell (LSC) generation and maintenance, little is known about the roles of microRNAs in LSC biology. Here we identify microRNAs that are differentially expressed in LSC-enriched cell fractions (c-kit(+)) in a mouse mod...

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Detalhes bibliográficos
Main Authors: Wong, Piu, Iwasaki, Masayuki, Somervaille, Tim C.P., Ficara, Francesca, Carico, Christine, Arnold, Christopher, Chen, Cheng-Zheng, Cleary, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862107/
https://ncbi.nlm.nih.gov/pubmed/20406979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3268
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