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COX-1-derived prostaglandin E(2) and EP1 receptors are required for the cerebrovascular dysfunction induced by angiotensin II
Prostaglandin E(2) (PGE(2) ) EP1 receptors (EP1R) may contribute to hypertension and related end-organ damage. Because of the key role of angiotensin II (AngII) in hypertension, we investigated the role of EP1R in the cerebrovascular alterations induced by AngII. Mice were equipped with a cranial wi...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2861995/ https://ncbi.nlm.nih.gov/pubmed/20194308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.109.145813 |
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