Efficient Human Hematopoietic Cell Transduction Using RD114- and GALV-Pseudotyped Retroviral Vectors Produced in Suspension and Serum-Free Media

Retroviral vectors derived from the Moloney murine leukemia virus have been used in successful and promising gene therapy clinical trials. However, platforms for their large-scale production must be further developed. As a proof of principle, we reported the generation of a packaging cell line that...

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Detalhes bibliográficos
Main Authors: Ghani, Karim, Wang, Xiuyan, de Campos-Lima, Pedro Otavio, Olszewska, Malgorzata, Kamen, Amine, Rivière, Isabelle, Caruso, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Scientific Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861952/
https://ncbi.nlm.nih.gov/pubmed/19453219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2009.001
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