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Improved transduction of human sheep repopulating cells by retrovirus vectors pseudotyped with feline leukemia virus type C or RD114 envelopes

Gene therapy for hematopoietic diseases has been hampered by the low frequency of transduction of human hematopoietic stem cells (HSCs) with retroviral vectors pseudotyped with amphotropic envelopes. We hypothesized that transduction could be increased by the use of retroviral vectors pseudotyped wi...

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Detalhes bibliográficos
Main Authors: Lucas, M. Lee, Seidel, Nancy E., Porada, Christopher D., Quigley, John G., Anderson, Stacie M., Malech, Harry L., Abkowitz, Janis L., Zanjani, Esmail D., Bodine, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895126/
https://ncbi.nlm.nih.gov/pubmed/15774617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-11-4491
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