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Recent Developments with Lipoprotein-Associated Phospholipase A(2) Inhibitors

Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is a calcium-independent phospholipase A(2) enzyme secreted by leukocytes and associated with circulating low-density lipoprotein and macrophages in atherosclerotic plaques. Until recently, the biological role of Lp-PLA(2) in atherosclerosis was...

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Autores principales: Chauffe, Ryan J., Wilensky, Robert L., Mohler, Emile R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861789/
https://ncbi.nlm.nih.gov/pubmed/20425270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11883-009-0076-9
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