Helicobacter pylori VacA Toxin/Subunit p34: Targeting of an Anion Channel to the Inner Mitochondrial Membrane

The vacuolating toxin VacA, released by Helicobacter pylori, is an important virulence factor in the pathogenesis of gastritis and gastroduodenal ulcers. VacA contains two subunits: The p58 subunit mediates entry into target cells, and the p34 subunit mediates targeting to mitochondria and is essent...

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Autors principals: Domańska, Grażyna, Motz, Christian, Meinecke, Michael, Harsman, Anke, Papatheodorou, Panagiotis, Reljic, Boris, Dian-Lothrop, Elke A., Galmiche, Antoine, Kepp, Oliver, Becker, Lars, Günnewig, Kathrin, Wagner, Richard, Rassow, Joachim
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861713/
https://ncbi.nlm.nih.gov/pubmed/20442789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000878
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