Helicobacter pylori VacA Toxin/Subunit p34: Targeting of an Anion Channel to the Inner Mitochondrial Membrane

The vacuolating toxin VacA, released by Helicobacter pylori, is an important virulence factor in the pathogenesis of gastritis and gastroduodenal ulcers. VacA contains two subunits: The p58 subunit mediates entry into target cells, and the p34 subunit mediates targeting to mitochondria and is essent...

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Detalhes bibliográficos
Main Authors: Domańska, Grażyna, Motz, Christian, Meinecke, Michael, Harsman, Anke, Papatheodorou, Panagiotis, Reljic, Boris, Dian-Lothrop, Elke A., Galmiche, Antoine, Kepp, Oliver, Becker, Lars, Günnewig, Kathrin, Wagner, Richard, Rassow, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861713/
https://ncbi.nlm.nih.gov/pubmed/20442789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000878
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