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Human Telomeres Are Hypersensitive to UV-Induced DNA Damage and Refractory to Repair

Telomeric repeats preserve genome integrity by stabilizing chromosomes, a function that appears to be important for both cancer and aging. In view of this critical role in genomic integrity, the telomere's own integrity should be of paramount importance to the cell. Ultraviolet light (UV), the...

詳細記述

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書誌詳細
主要な著者: Rochette, Patrick J., Brash, Douglas E.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861706/
https://ncbi.nlm.nih.gov/pubmed/20442874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000926
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