Spatial Distribution of Factor Xa, Thrombin, and Fibrin(ogen) on Thrombi at Venous Shear

BACKGROUND: The generation of thrombin is a critical process in the formation of venous thrombi. In isolated plasma under static conditions, phosphatidylserine (PS)-exposing platelets support coagulation factor activation and thrombin generation; however, their role in supporting coagulation factor...

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Autors principals: Berny, Michelle A., Munnix, Imke C. A., Auger, Jocelyn M., Schols, Saskia E. M., Cosemans, Judith M. E. M., Panizzi, Peter, Bock, Paul E., Watson, Steve P., McCarty, Owen J. T., Heemskerk, Johan W. M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861630/
https://ncbi.nlm.nih.gov/pubmed/20454680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010415
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