Spatial Distribution of Factor Xa, Thrombin, and Fibrin(ogen) on Thrombi at Venous Shear

BACKGROUND: The generation of thrombin is a critical process in the formation of venous thrombi. In isolated plasma under static conditions, phosphatidylserine (PS)-exposing platelets support coagulation factor activation and thrombin generation; however, their role in supporting coagulation factor...

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Bibliographic Details
Main Authors: Berny, Michelle A., Munnix, Imke C. A., Auger, Jocelyn M., Schols, Saskia E. M., Cosemans, Judith M. E. M., Panizzi, Peter, Bock, Paul E., Watson, Steve P., McCarty, Owen J. T., Heemskerk, Johan W. M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861630/
https://ncbi.nlm.nih.gov/pubmed/20454680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010415
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