Spatial Distribution of Factor Xa, Thrombin, and Fibrin(ogen) on Thrombi at Venous Shear

BACKGROUND: The generation of thrombin is a critical process in the formation of venous thrombi. In isolated plasma under static conditions, phosphatidylserine (PS)-exposing platelets support coagulation factor activation and thrombin generation; however, their role in supporting coagulation factor...

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Detalhes bibliográficos
Main Authors: Berny, Michelle A., Munnix, Imke C. A., Auger, Jocelyn M., Schols, Saskia E. M., Cosemans, Judith M. E. M., Panizzi, Peter, Bock, Paul E., Watson, Steve P., McCarty, Owen J. T., Heemskerk, Johan W. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861630/
https://ncbi.nlm.nih.gov/pubmed/20454680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010415
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