Spatial Distribution of Factor Xa, Thrombin, and Fibrin(ogen) on Thrombi at Venous Shear

BACKGROUND: The generation of thrombin is a critical process in the formation of venous thrombi. In isolated plasma under static conditions, phosphatidylserine (PS)-exposing platelets support coagulation factor activation and thrombin generation; however, their role in supporting coagulation factor...

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Bibliografiska uppgifter
Huvudupphovsmän: Berny, Michelle A., Munnix, Imke C. A., Auger, Jocelyn M., Schols, Saskia E. M., Cosemans, Judith M. E. M., Panizzi, Peter, Bock, Paul E., Watson, Steve P., McCarty, Owen J. T., Heemskerk, Johan W. M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2010
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861630/
https://ncbi.nlm.nih.gov/pubmed/20454680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010415
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