Endogenous TCR Recombination in TCR Tg Single RAG-Deficient Mice Uncovered by Robust In Vivo T Cell Activation and Selection

Recombination activating gene (RAG)-deficient TCR (T Cell Receptor) Tg (transgenic) mice are routinely used as sources of monoclonal T cells. We found that after the transfer of T cells from a RAG-2-deficient 5CC7 TCR Tg mice into allogeneic hosts we recovered a population of T cells expressing dive...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Montaudouin, Caroline, Boucontet, Laurent, Mailhé-Lembezat, Marie-Pierre, Mariotti-Ferrandiz, Maria-Encarnita, Louise, Anne, Six, Adrien, Freitas, Antonio A., Garcia, Sylvie
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861594/
https://ncbi.nlm.nih.gov/pubmed/20454452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010238
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki