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Potential Role of Tryptophan and Chloride in the Inhibition of Human Myeloperoxidase
Myeloperoxidase (MPO) binds H(2)O(2) in the absence and presence of chloride (Cl(−)) and catalyzes the formation of potent oxidants through 1e(−) and 2e(−) oxidation pathways. These potent oxidants have been implicated in the pathogenesis of various diseases including atherosclerosis, asthma, arthri...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2861567/ https://ncbi.nlm.nih.gov/pubmed/18279680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.01.003 |
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