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Analysis of the mechanism by which melatonin inhibits human eosinophil peroxidase

BACKGROUND AND PURPOSE: Eosinophil peroxidase (EPO) catalyses the formation of oxidants implicated in the pathogenesis of various respiratory diseases including allergy and asthma. Mechanisms for inhibiting EPO, once released, are poorly understood. The aim of this work is to determine the mechanism...

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Detalhes bibliográficos
Main Authors: Lu, T, Galijasevic, S, Abdulhamid, I, Abu-Soud, H M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483384/
https://ncbi.nlm.nih.gov/pubmed/18516076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.173
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