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Autoantibodies to the δ-Opioid Receptor Function as Opioid Agonists and Display Immunomodulatory Activity
In this report, we show that affinity purified human anti-Delta Opioid Receptor (DOR) autoantibodies from IVIG are specific to DOR and possess agonistic properties displayed by their ability to dramatically decrease forskolin stimulated cAMP accumulation. Anti-DOR autoantibody also caused phosphoryl...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2861486/ https://ncbi.nlm.nih.gov/pubmed/19879656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2009.10.007 |
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