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Case-only Genome-wide Interaction Study of Disease Risk, Prognosis and Treatment

Case-control genome-wide association (GWA) studies have facilitated the identification of susceptibility loci for many complex diseases; however, these studies are often not adequately powered to detect gene-environment (GxE) and gene-gene (GxG) interactions. Case-only studies are more efficient tha...

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Bibliographic Details
Main Authors: Pierce, Brandon L., Ahsan, Habibul
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861332/
https://ncbi.nlm.nih.gov/pubmed/19434715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20427
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