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Genome-wide “Pleiotropy Scan” Identifies HNF1A Region as a Novel Pancreatic Cancer Susceptibility Locus

In genome-wide association (GWA) studies (i.e., “GWAS”), hundreds of thousands of single nucleotide polymorphisms (SNPs) are tested for association with a disease trait. Typically, GWA studies give equal consideration to all SNPs tested, regardless of existing knowledge of a SNP’s functionality or b...

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Detalhes bibliográficos
Main Authors: Pierce, Brandon L., Ahsan, Habibul
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129443/
https://ncbi.nlm.nih.gov/pubmed/21498636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-0124
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