A Genome-Wide “Pleiotropy Scan” Does Not Identify New Susceptibility Loci for Estrogen Receptor Negative Breast Cancer

Approximately 15–30% of all breast cancer tumors are estrogen receptor negative (ER−). Compared with ER-positive (ER+) disease they have an earlier age at onset and worse prognosis. Despite the vast number of risk variants identified for numerous cancer types, only seven loci have been unambiguously...

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Main Authors: Campa, Daniele, Barrdahl, Myrto, Tsilidis, Konstantinos K., Severi, Gianluca, Diver, W. Ryan, Siddiq, Afshan, Chanock, Stephen, Hoover, Robert N., Ziegler, Regina G., Berg, Christine D., Buys, Saundra S., Haiman, Christopher A., Henderson, Brian E., Schumacher, Fredrick R., Le Marchand, Loïc, Flesch-Janys, Dieter, Lindström, Sara, Hunter, David J., Hankinson, Susan E., Willett, Walter C., Kraft, Peter, Cox, David G., Khaw, Kay-Tee, Tjønneland, Anne, Dossus, Laure, Trichopoulos, Dimitrios, Panico, Salvatore, van Gils, Carla H., Weiderpass, Elisabete, Barricarte, Aurelio, Sund, Malin, Gaudet, Mia M., Giles, Graham, Southey, Melissa, Baglietto, Laura, Chang-Claude, Jenny, Kaaks, Rudolf, Canzian, Federico
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921107/
https://ncbi.nlm.nih.gov/pubmed/24523857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085955
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