A Genome-Wide “Pleiotropy Scan” Does Not Identify New Susceptibility Loci for Estrogen Receptor Negative Breast Cancer

Approximately 15–30% of all breast cancer tumors are estrogen receptor negative (ER−). Compared with ER-positive (ER+) disease they have an earlier age at onset and worse prognosis. Despite the vast number of risk variants identified for numerous cancer types, only seven loci have been unambiguously...

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Main Authors: Campa, Daniele, Barrdahl, Myrto, Tsilidis, Konstantinos K., Severi, Gianluca, Diver, W. Ryan, Siddiq, Afshan, Chanock, Stephen, Hoover, Robert N., Ziegler, Regina G., Berg, Christine D., Buys, Saundra S., Haiman, Christopher A., Henderson, Brian E., Schumacher, Fredrick R., Le Marchand, Loïc, Flesch-Janys, Dieter, Lindström, Sara, Hunter, David J., Hankinson, Susan E., Willett, Walter C., Kraft, Peter, Cox, David G., Khaw, Kay-Tee, Tjønneland, Anne, Dossus, Laure, Trichopoulos, Dimitrios, Panico, Salvatore, van Gils, Carla H., Weiderpass, Elisabete, Barricarte, Aurelio, Sund, Malin, Gaudet, Mia M., Giles, Graham, Southey, Melissa, Baglietto, Laura, Chang-Claude, Jenny, Kaaks, Rudolf, Canzian, Federico
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921107/
https://ncbi.nlm.nih.gov/pubmed/24523857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085955
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