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Mice Expressing the A53T Mutant Form of Human Alpha-Synuclein Exhibit Hyperactivity and Reduced Anxiety-Like Behavior

Genetic mutations associated with α-synuclein (α-Syn) are implicated in the pathogenesis of Parkinson’s disease (PD). PD is primarily a movement disorder, but patients are known to experience anxiety and other mood disorders. In this study, we examined the effect of the hA53T mutation during develop...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Graham, Dianca R., Sidhu, Anita
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861296/
https://ncbi.nlm.nih.gov/pubmed/20077428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22331
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