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Mice Expressing the A53T Mutant Form of Human Alpha-Synuclein Exhibit Hyperactivity and Reduced Anxiety-Like Behavior
Genetic mutations associated with α-synuclein (α-Syn) are implicated in the pathogenesis of Parkinson’s disease (PD). PD is primarily a movement disorder, but patients are known to experience anxiety and other mood disorders. In this study, we examined the effect of the hA53T mutation during develop...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2861296/ https://ncbi.nlm.nih.gov/pubmed/20077428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22331 |
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