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Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells
The spindle checkpoint generates a “wait anaphase” signal at unattached kinetochores to prevent premature anaphase onset. Kinetochore-localized dynein is thought to silence the checkpoint by transporting checkpoint proteins from microtubule-attached kinetochores to spindle poles. Throughout metazoan...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2861194/ https://ncbi.nlm.nih.gov/pubmed/20439434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1886810 |
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