Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells

The spindle checkpoint generates a “wait anaphase” signal at unattached kinetochores to prevent premature anaphase onset. Kinetochore-localized dynein is thought to silence the checkpoint by transporting checkpoint proteins from microtubule-attached kinetochores to spindle poles. Throughout metazoan...

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Autors principals: Gassmann, Reto, Holland, Andrew J., Varma, Dileep, Wan, Xiaohu, Çivril, Filiz, Cleveland, Don W., Oegema, Karen, Salmon, Edward D., Desai, Arshad
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2010
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861194/
https://ncbi.nlm.nih.gov/pubmed/20439434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1886810
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