Dimethylarginine Dimethylaminohydrolase Overexpression Ameliorates Atherosclerosis in Apolipoprotein E-Deficient Mice by Lowering Asymmetric Dimethylarginine

Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, is increasingly recognized as a novel biomarker in cardiovascular disease. To date, it remains unclear whether elevated ADMA levels are merely associated with cardiovascular risk or whether this molecule is of func...

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Détails bibliographiques
Auteurs principaux: Jacobi, Johannes, Maas, Renke, Cardounel, Arturo J., Arend, Michaela, Pope, Arthur J., Cordasic, Nada, Heusinger-Ribeiro, Juliane, Atzler, Dorothee, Strobel, Joachim, Schwedhelm, Edzard, Böger, Rainer H., Hilgers, Karl F.
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2010
Sujets:
Regular Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861120/
https://ncbi.nlm.nih.gov/pubmed/20348244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090614
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