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Effect of Lowering Asymmetric Dimethylarginine (ADMA) on Vascular Pathology in Atherosclerotic ApoE-Deficient Mice with Reduced Renal Mass

The purpose of the work was to study the impact of the endogenous nitric oxide synthase (NOS) inhibitor asymmetric dimethylarginine (ADMA) and its degrading enzyme, dimethylarginine dimethylaminohydrolase (DDAH1), on atherosclerosis in subtotally nephrectomized (SNX) ApoE-deficient mice. Male DDAH1...

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Autors principals: Jacobi, Johannes, Maas, Renke, Arend, Michaela, Cordasic, Nada, Hilgers, Karl F.
Format: Artigo
Idioma:Inglês
Publicat: Molecular Diversity Preservation International (MDPI) 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013579/
https://ncbi.nlm.nih.gov/pubmed/24690995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms15045522
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