Reduction of IKKα Expression Promotes Chronic Ultraviolet B Exposure-Induced Skin Inflammation and Carcinogenesis

Ultraviolet B light (UVB) is a common cause of human skin cancer. UVB irradiation induces mutations in the tumor suppressor p53 gene as well as chronic inflammation, which are both essential for UVB carcinogenesis. Inhibitor of nuclear factor κB kinase-α (IKKα) plays an important role in maintaining...

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Detalhes bibliográficos
Main Authors: Xia, Xiaojun, Park, Eunmi, Liu, Bigang, Willette-Brown, Jami, Gong, Wanghua, Wang, Jiming, Mitchell, David, Fischer, Susan M., Hu, Yinling
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861114/
https://ncbi.nlm.nih.gov/pubmed/20304950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.091041
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