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IKKα Is Required to Maintain Skin Homeostasis and Prevent Skin Cancer

It has long been known that excessive mitotic activity due to H-Ras can block keratinocyte differentiation and cause skin cancer. It is not clear whether there are any innate surveillants that are able to ensure that keratinocytes undergo terminal differentiation, preventing the disease. IKKα induce...

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Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Liu, Bigang, Xia, Xiaojun, Zhu, Feng, Park, Eunmi, Carbajal, Steve, Kiguchi, Kaoru, DiGiovanni, John, Fischer, Susan, Hu, Yinling
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263012/
https://ncbi.nlm.nih.gov/pubmed/18772111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2008.07.017
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