Reduction of IKKα Expression Promotes Chronic Ultraviolet B Exposure-Induced Skin Inflammation and Carcinogenesis

Ultraviolet B light (UVB) is a common cause of human skin cancer. UVB irradiation induces mutations in the tumor suppressor p53 gene as well as chronic inflammation, which are both essential for UVB carcinogenesis. Inhibitor of nuclear factor κB kinase-α (IKKα) plays an important role in maintaining...

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Bibliografiske detaljer
Main Authors: Xia, Xiaojun, Park, Eunmi, Liu, Bigang, Willette-Brown, Jami, Gong, Wanghua, Wang, Jiming, Mitchell, David, Fischer, Susan M., Hu, Yinling
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2010
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861114/
https://ncbi.nlm.nih.gov/pubmed/20304950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.091041
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