Reduction of IKKα Expression Promotes Chronic Ultraviolet B Exposure-Induced Skin Inflammation and Carcinogenesis

Ultraviolet B light (UVB) is a common cause of human skin cancer. UVB irradiation induces mutations in the tumor suppressor p53 gene as well as chronic inflammation, which are both essential for UVB carcinogenesis. Inhibitor of nuclear factor κB kinase-α (IKKα) plays an important role in maintaining...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Xia, Xiaojun, Park, Eunmi, Liu, Bigang, Willette-Brown, Jami, Gong, Wanghua, Wang, Jiming, Mitchell, David, Fischer, Susan M., Hu, Yinling
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2010
Предметы:
Regular Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861114/
https://ncbi.nlm.nih.gov/pubmed/20304950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.091041
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы