Forced Expression of Methionine Adenosyltransferase 1A in Human Hepatoma Cells Suppresses in Vivo Tumorigenicity in Mice

Methionine adenosyltransferase (MAT) catalyzes the synthesis of S-adenosylmethionine, the principal methyl donor, and is encoded by MAT1A and MAT2A in mammals. Normal liver expresses MAT1A, which is silenced in hepatocellular carcinoma. We have shown that hepatoma cells overexpressing MAT1A grew slo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Li, Jiaping, Ramani, Komal, Sun, Zhanfeng, Zee, Chishing, Grant, Edward G., Yang, Heping, Xia, Meng, Oh, Pilsoo, Ko, Kwangsuk, Mato, José M., Lu, Shelly C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Investigative Pathology 2010
Gaiak:
Regular Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861110/
https://ncbi.nlm.nih.gov/pubmed/20363925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090810
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