The Tetraspanin CD37 Protects Against Glomerular IgA Deposition and Renal Pathology

The tetraspanin protein CD37 is a leukocyte-specific transmembrane protein that is highly expressed on B cells. CD37-deficient (CD37(−/−)) mice exhibit a 15-fold increased level of immunoglobulin A (IgA) in serum and elevated numbers of IgA(+) plasma cells in lymphoid organs. Here, we report that CD...

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Detaylı Bibliyografya
Asıl Yazarlar: Rops, Angelique L., Figdor, Carl G., van der Schaaf, Alie, Tamboer, Wim P., Bakker, Marinka A., Berden, Jo H., Dijkman, Henry B.P.M., Steenbergen, Eric J., van der Vlag, Johan, van Spriel, Annemiek B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Investigative Pathology 2010
Konular:
Regular Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861084/
https://ncbi.nlm.nih.gov/pubmed/20348240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090770
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