The Tetraspanin CD37 Protects Against Glomerular IgA Deposition and Renal Pathology

The tetraspanin protein CD37 is a leukocyte-specific transmembrane protein that is highly expressed on B cells. CD37-deficient (CD37(−/−)) mice exhibit a 15-fold increased level of immunoglobulin A (IgA) in serum and elevated numbers of IgA(+) plasma cells in lymphoid organs. Here, we report that CD...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rops, Angelique L., Figdor, Carl G., van der Schaaf, Alie, Tamboer, Wim P., Bakker, Marinka A., Berden, Jo H., Dijkman, Henry B.P.M., Steenbergen, Eric J., van der Vlag, Johan, van Spriel, Annemiek B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Investigative Pathology 2010
Pynciau:
Regular Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861084/
https://ncbi.nlm.nih.gov/pubmed/20348240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090770
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