The Tetraspanin CD37 Protects Against Glomerular IgA Deposition and Renal Pathology

The tetraspanin protein CD37 is a leukocyte-specific transmembrane protein that is highly expressed on B cells. CD37-deficient (CD37(−/−)) mice exhibit a 15-fold increased level of immunoglobulin A (IgA) in serum and elevated numbers of IgA(+) plasma cells in lymphoid organs. Here, we report that CD...

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Main Authors: Rops, Angelique L., Figdor, Carl G., van der Schaaf, Alie, Tamboer, Wim P., Bakker, Marinka A., Berden, Jo H., Dijkman, Henry B.P.M., Steenbergen, Eric J., van der Vlag, Johan, van Spriel, Annemiek B.
格式: Artigo
語言:Inglês
出版: American Society for Investigative Pathology 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861084/
https://ncbi.nlm.nih.gov/pubmed/20348240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090770
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