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The Tetraspanin CD37 Protects Against Glomerular IgA Deposition and Renal Pathology
The tetraspanin protein CD37 is a leukocyte-specific transmembrane protein that is highly expressed on B cells. CD37-deficient (CD37(−/−)) mice exhibit a 15-fold increased level of immunoglobulin A (IgA) in serum and elevated numbers of IgA(+) plasma cells in lymphoid organs. Here, we report that CD...
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Κύριοι συγγραφείς: | , , , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
American Society for Investigative Pathology
2010
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2861084/ https://ncbi.nlm.nih.gov/pubmed/20348240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090770 |
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