Midkine, heparin-binding growth factor, blocks kainic acid-induced seizure and neuronal cell death in mouse hippocampus

BACKGROUND: Midkine (MK), a member of the heparin-binding growth factor family, which includes MK and pleiotrophin, is known to possess neurotrophic and neuroprotective properties in the central nervous system. Previous studies have shown that MK is an effective neuroprotective agent in reducing ret...

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Bibliografiske detaljer
Main Authors: Kim, Yun B, Ryu, Jae K, Lee, Hong J, Lim, In J, Park, Dongsun, Lee, Min C, Kim, Seung U
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861065/
https://ncbi.nlm.nih.gov/pubmed/20346117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-11-42
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