Midkine, heparin-binding growth factor, blocks kainic acid-induced seizure and neuronal cell death in mouse hippocampus

BACKGROUND: Midkine (MK), a member of the heparin-binding growth factor family, which includes MK and pleiotrophin, is known to possess neurotrophic and neuroprotective properties in the central nervous system. Previous studies have shown that MK is an effective neuroprotective agent in reducing ret...

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Main Authors: Kim, Yun B, Ryu, Jae K, Lee, Hong J, Lim, In J, Park, Dongsun, Lee, Min C, Kim, Seung U
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Research article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861065/
https://ncbi.nlm.nih.gov/pubmed/20346117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-11-42
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