HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype

Breast cancer 1, early onset (BRCA1) expression is often reduced in sporadic breast tumors, even in the absence of BRCA1 genetic modifications, but the molecular basis for this is unknown. In this study, we identified homeobox A9 (HOXA9) as a gene frequently downregulated in human breast cancers and...

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Главные авторы: Gilbert, Penney M., Mouw, Janna K., Unger, Meredith A., Lakins, Johnathon N., Gbegnon, Mawuse K., Clemmer, Virginia B., Benezra, Miriam, Licht, Jonathan D., Boudreau, Nancy J., Tsai, Kelvin K.C., Welm, Alana L., Feldman, Michael D., Weber, Barbara L., Weaver, Valerie M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2010
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860938/
https://ncbi.nlm.nih.gov/pubmed/20389018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39534
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