Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation

The folate pathway plays a crucial role in the regeneration and repair of the adult CNS after injury. Here, we have shown in rodents that such repair occurs at least in part through DNA methylation. In animals with combined spinal cord and sciatic nerve injury, folate-mediated CNS axon regeneration...

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Autori principali: Iskandar, Bermans J., Rizk, Elias, Meier, Brenton, Hariharan, Nithya, Bottiglieri, Teodoro, Finnell, Richard H., Jarrard, David F., Banerjee, Ruma V., Skene, J.H. Pate, Nelson, Aaron, Patel, Nirav, Gherasim, Carmen, Simon, Kathleen, Cook, Thomas D., Hogan, Kirk J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860927/
https://ncbi.nlm.nih.gov/pubmed/20424322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40000
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