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Decyanation of vitamin B(12) by a trafficking chaperone

The mystery of how the cyanide group in vitamin B(12) or cyanocobalamin, discovered 60 years ago, is removed, has been solved by the demonstration that the trafficking chaperone, MMACHC, catalyzes a reductive decyanation reaction. Electrons transferred from NADPH via cytosolic flavoprotein oxidoredu...

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Detalhes bibliográficos
Main Authors: Kim, Jihoe, Gherasim, Carmen, Banerjee, Ruma
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567227/
https://ncbi.nlm.nih.gov/pubmed/18779575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805989105
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