Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation

The folate pathway plays a crucial role in the regeneration and repair of the adult CNS after injury. Here, we have shown in rodents that such repair occurs at least in part through DNA methylation. In animals with combined spinal cord and sciatic nerve injury, folate-mediated CNS axon regeneration...

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Detalhes bibliográficos
Main Authors: Iskandar, Bermans J., Rizk, Elias, Meier, Brenton, Hariharan, Nithya, Bottiglieri, Teodoro, Finnell, Richard H., Jarrard, David F., Banerjee, Ruma V., Skene, J.H. Pate, Nelson, Aaron, Patel, Nirav, Gherasim, Carmen, Simon, Kathleen, Cook, Thomas D., Hogan, Kirk J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860927/
https://ncbi.nlm.nih.gov/pubmed/20424322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40000
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