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Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents
Although many animal studies indicate insulin has cardioprotective effects, clinical studies suggest a link between insulin resistance (hyperinsulinemia) and heart failure (HF). Here we have demonstrated that excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure ov...
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Main Authors: | , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860916/ https://ncbi.nlm.nih.gov/pubmed/20407209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40096 |
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