Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk

We conducted dense linkage disequilibrium (LD) mapping of a series of 25 genes putatively involved in lipid metabolism in 1567 dementia cases [including 1270 with Alzheimer disease (AD)] and 2203 Swedish controls. Across a total of 448 tested genetic markers, the strongest evidence of association wa...

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Hlavní autoři: Reynolds, Chandra A., Hong, Mun-Gwan, Eriksson, Ulrika K., Blennow, Kaj, Wiklund, Fredrik, Johansson, Boo, Malmberg, Bo, Berg, Stig, Alexeyenko, Andrey, Grönberg, Henrik, Gatz, Margaret, Pedersen, Nancy L., Prince, Jonathan A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
Association Studies Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860895/
https://ncbi.nlm.nih.gov/pubmed/20167577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq079
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