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Evidence that the gene encoding insulin degrading enzyme influences human lifespan

Studies in model organisms have demonstrated that components of insulin and insulin-like signaling pathways are involved in the regulation of lifespan but the relevance of those findings to humans has remained obscure. Here we provide evidence suggesting that variants of the gene encoding insulin-de...

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Detalhes bibliográficos
Main Authors: Hong, Mun-Gwan, Reynolds, Chandra, Gatz, Margaret, Johansson, Boo, Palmer, Jennifer C., Gu, Harvest F., Blennow, Kaj, Kehoe, Patrick G., de Faire, Ulf, Pedersen, Nancy L., Prince, Jonathan A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574758/
https://ncbi.nlm.nih.gov/pubmed/18448515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn137
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