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A DNA damage-activated checkpoint kinase phosphorylates tau and enhances tau-induced neurodegeneration
Hyperphosphorylation of the microtubule associated protein tau is detected in the brains of individuals with a range of neurodegenerative diseases including Alzheimer's disease (AD). An imbalance in phosphorylation and/or dephosphorylation of tau at disease-related sites has been suggested to i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860892/ https://ncbi.nlm.nih.gov/pubmed/20159774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq068 |
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