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Thoracic aortic disease in tuberous sclerosis complex: molecular pathogenesis and potential therapies in Tsc2(+/−) mice
Tuberous sclerosis complex (TSC) is a genetic disorder with pleiotropic manifestations caused by heterozygous mutations in either TSC1 or TSC2. One of the less investigated complications of TSC is the formation of aneurysms of the descending aorta, which are characterized on pathologic examination b...
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| Glavni autori: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860890/ https://ncbi.nlm.nih.gov/pubmed/20159776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq066 |
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