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Bioactivities of Simplified Adociaquinone B and Naphthoquinone Derivatives against Cdc25B, MKP-1, and MKP-3 Phosphatases
Some simplified adociaquinone B analogs and a series of 1,4-naphthoquinone derivatives were synthesized and tested against the three enzymes Cdc25B, MKP-1, and MKP-3. Cdc25B and MKP1 in particular are enzymes overexpressed in human cancer cells, and they represent potential molecular targets for nov...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860877/ https://ncbi.nlm.nih.gov/pubmed/19028102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.10.090 |
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