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Factors that Determine the Efficiency of HIV-1 Strand Transfer Initiated at a Specific Site

HIV-1 employs strand transfer for recombination between the two viral genomes. We previously provided evidence that strand transfer proceeds by an invasion-mediated mechanism, in which a DNA segment on the original RNA template is invaded by a second RNA template at a gap site. The initial RNA-DNA h...

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Bibliographic Details
Main Authors: Rigby, Sean T., Van Nostrand, Keith P., Rose, April E., Gorelick, Robert J., Mathews, David H., Bambara, Robert A.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860860/
https://ncbi.nlm.nih.gov/pubmed/19853618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.10.036
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