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Signal peptide peptidase (SPP) assembles with substrates and misfolded membrane proteins into distinct oligomeric complexes

SPP (signal peptide peptidase) is an aspartyl intramembrane cleaving protease, which processes a subset of signal peptides, and is linked to the quality control of ER (endoplasmic reticulum) membrane proteins. We analysed SPP interactions with signal peptides and other membrane proteins by co-immuno...

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Bibliographische Detailangaben
Hauptverfasser: Schrul, Bianca, Kapp, Katja, Sinning, Irmgard, Dobberstein, Bernhard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860808/
https://ncbi.nlm.nih.gov/pubmed/20196774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20091005
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