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Giant osteoclasts after long-term bisphosphonate therapy: diagnostic challenges

BACKGROUND: A 55-year-old woman with a 5-year history of osteoporosis treated for 4 years with an oral aminobisphosphonate presented with a recent vertebral fracture. A bone biopsy specimen revealed giant osteoclasts with more than 40 nuclear profiles. INVESTIGATIONS: Bone mineral density determinat...

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Hlavní autoři: Jain, Nidhi, Weinstein, Robert S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860596/
https://ncbi.nlm.nih.gov/pubmed/19491914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrrheum.2009.87
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