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Mechanistic basis for LQT1 caused by S3 mutations in the KCNQ1 subunit of I(Ks)
Long QT interval syndrome (LQTS) type 1 (LQT1) has been reported to arise from mutations in the S3 domain of KCNQ1, but none of the seven S3 mutations in the literature have been characterized with respect to trafficking or biophysical deficiencies. Surface channel expression was studied using a pro...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The Rockefeller University Press
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860592/ https://ncbi.nlm.nih.gov/pubmed/20421371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910351 |
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