High Expression of Lymphocyte-Activation Gene 3 (LAG3) in Chronic Lymphocytic Leukemia Cells Is Associated with Unmutated Immunoglobulin Variable Heavy Chain Region (IGHV) Gene and Reduced Treatment-Free Survival

Chronic lymphocytic leukemia (CLL) is characterized by a monoclonal expansion of mature B-lymphocytes. Mutational status of the immunoglobulin variable heavy chain region (IGHV) gene stratifies CLL patients into two prognostic groups. We performed microarray analysis of CLL cells using the Agilent p...

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Hauptverfasser: Kotaskova, Jana, Tichy, Boris, Trbusek, Martin, Francova, Hana Skuhrova, Kabathova, Jitka, Malcikova, Jitka, Doubek, Michael, Brychtova, Yvona, Mayer, Jiri, Pospisilova, Sarka
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860469/
https://ncbi.nlm.nih.gov/pubmed/20228263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2010.090100
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